Geriatric Drug Review -- Flexeril
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What is this Drug
Flexeril - Cyclobenzaprine (sye-kloe-BEN-za-preen) is used to help relax certain muscles in your body. It helps relieve the pain, stiffness, and discomfort caused by strains, sprains, or injuries to y
our muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. Cyclobenzaprine acts on t
he central nervous system (CNS) to produce its muscle relaxant effects. Its actions on the CNS may also cause some of this medicine's side effects.
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Precautions Before Using This Medicine
Before taking cyclobenzaprine,
- tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking cyclobenzaprine, call your doctor im
mediately.
- you should know that this drug may make you drowsy. Do not drive a car or operate machinery until you know how cyclobenzaprine affects you.
- remember that alcohol can add to th
e drowsiness caused by this drug.
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Symptoms of overdose
Convulsions (seizures); drowsiness (severe) ; dry, hot, flushed skin; fast or irregular heartbeat; hallucinations (seeing, hearing, or feeling things that are not there); increase or decrease in
body temperature; troubled breathing; unexplained muscle stiffness; unusual nervousness or restlessness (severe); vomiting (occurring together with other symptoms of overdose)
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What special precautions should I follow?
The effects of Flexeril during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known if Flexeril appears in breast
milk. However, cyclobenzaprine is related to tricyclic antidepressants, and some of those drugs do appear in breast milk. If this medication is essential to your health, your doctor may advise you to
discontinue breastfeeding your baby until your treatment is finished.
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Possible food and drug interactions when taking this medication
Serious, potentially fatal reactions may occur if you take Flexeril with an antidepressant drug known as an MAO inhibitor (such as Nardil, Parnate) or if it has been less than 2 weeks since you last t
ook an MAO inhibitor. You should closely follow your doctor's advice regarding discontinuation of MAO inhibitors before taking Flexeril.
Avoid alcoholic beverages while taking Flexeril.
<
br> If Flexeril is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Flexeril with
the following:
- Guanethidine and other high blood pressure drugs
- Other drugs that slow the central nervous system
- Tramadol (Ultram)
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Side Effects
Flexeril may cause you to become drowsy or less alert; therefore, you should not drive or operate dangerous machinery or participate in any hazardous activity that requires full mental alertness until
you know how this drug affects you.
You should use Flexeril with caution if you have ever been unable to urinate or if you have ever had the eye condition called glaucoma.
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