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Drug Interactions
If Imitrex is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is important to check with your doctor before combining Imitrex with the following:
- Drugs classified as MAO inhibitors, including the antidepressants Nardil and Parnate - Ergot-containing drugs such as Cafergot and Ergostat - Fluoxetine (Prozac) - Fluvoxamine (
Luvox) - Paroxetine (Paxil) - Sertraline (Zoloft)
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Why is this medication prescribed?
Imitrex is prescribed for the treatment of a migraine attack with or without the presence of an aura (visual disturbances, usually sensations of halos or flickering lights, which precede an attack). T
he injectable form is also used to relieve cluster headache attacks. (Cluster headaches come on in waves, then disappear for long periods of time. They are limited to one side of the head, and occur m
ainly in men.) Imitrex cuts headaches short. It will not reduce the number of attacks you experience
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Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately. Symptoms of Imitrex overdose may include: - Bluish tinge to
the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor
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How should you take this medication?
Do not use .Imitrex for a headache that is different from your usual migraines . Instead, check with your doctor. To relieve your migraine as soon as possible, use .Imitrex as soon as the hea
dache pain begins. Even if you get warning signals of a coming migraine (an aura), you should wait until the headache pain starts before using .Imitrex. Using .Imitrex during the aura probably will no
t prevent the headache from occurring. However, even if you do not use .Imitrex until your migraine has been present for several hours, the medicine will still work. Lying down in a quiet, da
rk room for a while after you use this medicine may help relieve your migraine.
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Precautions while Using this Medicine
tell your doctor and pharmacist what prescription and nonprescription medications you are taking, especially fluoxetine (Prozac, Sarafem), fluvoxamine (Luvox), paroxetine (Paxil), sertraline (Zoloft),
and vitamins. If you have taken an MAO inhibitor [phenelzine (Nardil) or tranylcypromine (Parnate)] during the past 2 weeks, do not take sumatriptan. If you have taken another medication for migraine
headaches such as dihydroergotamine (D.H.E. 45, Migranal), methysergide (Sansert), naratriptan (Amerge), rizatriptan (Maxalt, Maxalt-MLT), or zolmitriptan (Zomig) during the past 24 hours, do not tak
e sumatriptan.
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Before Using This Medicine
The effects of Imitrex during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Imitrex does appear in breast milk and could a
ffect a nursing infant. If this medication is essential to your health, your doctor may advise you to discontinue breastfeeding until your treatment with Imitrex is finished.
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